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Immune Checkpoint Inhibitor-Induced Sarcoidosis-Like Reaction Mimicking Pulmonary Metastasis: A Case Report
Mari Sawada1, Yoshiko Kurose1, Yoshifumi Ochi1
1Department of Gynecology, Kurashiki Medical Center, Kurashiki, JPN.
Cureus
|June 1, 2026
Summary
Immune checkpoint inhibitors like pembrolizumab can cause sarcoidosis-like reactions. Recognizing these reactions is crucial to avoid misdiagnosing them as cancer progression and to ensure continued effective immunotherapy.
Area of Science:
- Oncology
- Immunology
- Pulmonology
Background:
- Immune checkpoint inhibitors (ICIs) are crucial in cancer treatment.
- ICIs can cause immune-related adverse events, including sarcoidosis-like reactions.
- These reactions can mimic metastatic disease, posing diagnostic challenges.
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