Letter to the Editor: Bridging the immunization gap in pediatric autoimmune disorders - insights from inflammatory...

Autoimmune diseases represent serious conditions characterized by immune dysregulation, which compromises the body's defense mechanisms and affects responses to infections and Vaccines. In addition to this, the treatment of these diseases involves mostly immunosuppressant's. I read with great interest the study published in the World Journal of Clinical Pediatrics by Makarova et al, examining vaccines and antibody levels in children with inflammatory bowel disease (IBD), with a focus on enhancing children's immune responses. Children with autoimmune diseases often show poor response to vaccines, which is attributed to their health condition and the immunosuppressive drugs used in treatment. One of the effective ways to protect these people in general and the children in specific is to follow personalized vaccination plans, or as mentioned in the research being discussed, to carry out revaccination and conduct serology tests and immunoglobulin G to ensure the effectiveness of vaccination plans. Those with diseases similar to IBD, and related diseases should conduct periodic checks after vaccination.