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Published on: October 11, 2024
Constrictive pericarditis after lung transplantation: A single-center cohort
Rimsha Ahmad1, Sushil A Luis2, Jae K Oh2
1Department of Internal Medicine, Westchester Medical Center, New York Medical College, Valhalla, New York.
Constrictive pericarditis is a rare but serious complication after lung transplantation. Early diagnosis requires a high index of suspicion due to nonspecific symptoms and the need for invasive hemodynamic confirmation.
Area of Science:
- Cardiology
- Thoracic Surgery
- Pulmonary Medicine
Background:
- Constrictive pericarditis is a known complication post-cardiac surgery.
- It is rarely reported after lung transplantation, presenting diagnostic challenges.
- Limited data exists on its presentation and management in lung transplant recipients.
Purpose of the Study:
- To investigate the incidence and characteristics of constrictive pericarditis following lung transplantation.
- To identify diagnostic challenges and outcomes in this patient population.
Main Methods:
- Retrospective review of lung transplant recipients at Mayo Clinic (2000-2022).
- Identification of patients who developed constrictive pericarditis post-transplantation.
- Collection of demographic, echocardiographic, hemodynamic, and surgical data.
Main Results:
- 1.6% (15/960) of lung transplant recipients developed constrictive pericarditis; 0.5% (5/960) required pericardiectomy.
- Constrictive pericarditis occurred a median of 8.4 months post-transplant, presenting with dyspnea and pleural effusions.
- Echocardiography and right heart catheterization revealed characteristic findings, with 2-year survival after pericardiectomy at 60%.
Conclusions:
- Constrictive pericarditis is an uncommon yet significant complication after lung transplantation.
- Diagnosis is challenging due to nonspecific symptoms and potential limitations of echocardiography.
- A high index of suspicion and invasive hemodynamic confirmation are crucial for diagnosis.
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