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Updated: Jun 2, 2026
06:31
Precision Implementation of Minimal Erythema Dose (MED) Testing to Assess Individual Variation in Human Inflammatory Response
Published on: October 3, 2019
Probable metformin-associated erythema multiforme: a case report and practical reference to causality assessment
1Department of Neurology, The Central Hospital of Xiangtan (The Affiliated Hospital of Hunan University), Xiangtan, Hunan, China.
Frontiers in Endocrinology
|June 1, 2026
Summary
Metformin, a common type 2 diabetes drug, can rarely cause erythema multiforme, a specific skin reaction. This case highlights the importance of considering metformin when diagnosing drug-induced rashes.
Area of Science:
- Dermatology
- Endocrinology
- Clinical Pharmacology
Background:
- Metformin is a primary treatment for type 2 diabetes mellitus.
- Cutaneous adverse reactions to metformin are rare but varied.
- Erythema multiforme (EM) is an uncommon manifestation of metformin hypersensitivity.
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