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Related Experiment Video

Updated: Jun 2, 2026

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
03:27

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation

Published on: January 31, 2025

Perspective on Intraoperative Real-Time Biliary Tract Navigation: From Radiological to Fluorescent Imaging.

Chuxing Chai1, Tze Cin Owyong2, Yining Zhang3

  • 1Department of Hepatobiliary Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China.

Chemical & Biomedical Imaging
|June 1, 2026
PubMed
Summary

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This summary is machine-generated.

Accurate biliary anatomy identification is crucial in surgery to prevent bile duct injuries. Fluorescence-guided surgery using indocyanine green offers a safer, radiation-free alternative for real-time visualization, improving patient outcomes.

Area of Science:

  • Hepatobiliary Surgery
  • Surgical Navigation
  • Medical Imaging

Background:

  • Misidentification of biliary anatomy is the primary cause of bile duct injuries in hepatobiliary surgery.
  • Traditional methods like visual inspection and cholangiography have limitations including anatomical variability and radiation exposure.

Purpose of the Study:

  • To highlight the challenges in biliary navigation during surgery.
  • To review the potential of fluorescence-guided surgery (FGS) for improved visualization.
  • To discuss advancements in imaging technologies for enhanced surgical precision.

Main Methods:

  • Review of current clinical challenges in biliary anatomy identification.
  • Exploration of near-infrared fluorescence imaging with indocyanine green (ICG).
Keywords:
biliary tract imagingfluorescence cholangiographyfluorescence-guided surgeryindocyanine greenintraoperative cholangiographylaparoscopic cholecystectomynear-infrared imaging

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Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture
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Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture

Published on: November 25, 2025

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Last Updated: Jun 2, 2026

The Role of Indocyanine Green Fluorescence in Complex Laparoscopic Cholecystectomy Navigation
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Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture
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Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture

Published on: November 25, 2025

  • Discussion of next-generation fluorophores and imaging platforms.

    • Main Results:

    • Fluorescence-guided surgery offers real-time, low-toxicity visualization of biliary structures.
    • Emerging technologies promise to enhance intraoperative precision and reduce radiation reliance.
    • ICG provides a viable alternative to traditional methods for biliary visualization.

    Conclusions:

    • Advancements in fluorescence imaging can significantly improve patient safety in hepatobiliary surgery.
    • Developing new tools for FGS is essential to overcome current limitations in biliary navigation.
    • Enhanced visualization techniques are key to reducing bile duct injuries and improving surgical outcomes.