Machine Learning-Based Identification and Validation of PYCR1 and PYGM as Prognostic Biomarkers for Osteosarcoma

Guoyong Xu1, Chong Liu1,2, Jiang Xue1

  • 1Guangxi Medical University, The First Clinical Medical College, Nanning, P. R. China.

Summary

This study identifies Pyrroline-5-carboxylate reductase 1 (PYCR1) and glycogen phosphorylase, muscle-associated (PYGM) as potential prognostic biomarkers for osteosarcoma (OS). PYCR1 is upregulated and linked to poor prognosis, while PYGM shows complex expression patterns.

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