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Related Concept Videos

Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
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Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-IV: Nursing Management01:30

Asthma-IV: Nursing Management

The nursing management of asthma is a comprehensive approach that relies heavily on the expertise and dedication of healthcare professionals. It involves thorough assessment, accurate diagnosis, strategic planning, effective implementation, and diligent evaluation. By meticulously following this step-by-step process, healthcare professionals play a crucial role in providing the best possible care and treatment for patients with asthma, enhancing their overall health and well-being.
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Asthma-IV: Diagnostic and Management01:30

Asthma-IV: Diagnostic and Management

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Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...

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Updated: Jun 2, 2026

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Work-Related Asthma: An Occupational Medicine Perspective.

Yangwoo Kim1,2, Inah Kim3,4, Jaechul Song3,5

  • 1Department of Occupational and Environmental Medicine, Inha University Hospital, Incheon, Korea.

Allergy, Asthma & Immunology Research
|June 1, 2026
PubMed
Summary

Work-related asthma (WRA) is a common occupational respiratory disease. Korean surveillance shows underdiagnosis and a unique agent profile, highlighting the need for improved clinical suspicion and workplace assessments.

Keywords:
Occupational asthmaRepublic of Koreaepidemiologyisocyanatesoccupational diseasespublic health surveillanceworkers' compensation

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Area of Science:

  • Occupational Medicine
  • Respiratory Medicine
  • Epidemiology

Background:

  • Work-related asthma (WRA) is a significant occupational respiratory disease, with 10-25% of adult asthma cases linked to workplace exposures.
  • Preventable nature of WRA underscores the importance of occupational health surveillance and management.

Purpose of the Study:

  • To review the epidemiology, causative agents, pathogenesis, clinical evaluation, management, and prevention of WRA.
  • To emphasize Korean surveillance data and compare it with international estimates.
  • To highlight challenges in WRA diagnosis and prognosis.

Main Methods:

  • Analysis of the Korea Work-related Asthma Surveillance program data (2004-2009).
  • Examination of temporal trends in causative agents, particularly isocyanates.
  • Review of workers' compensation data (2013-2023) for underdiagnosis insights.

Main Results:

  • The Korean surveillance program identified a low incidence (3.31/million workers), indicating a significant detection gap compared to European estimates.
  • Isocyanates were a prominent causative agent (46.6%) in Korean cases, reflecting the furniture industry's influence.
  • Temporal trends showed a decrease in isocyanate-related WRA cases, suggesting successful prevention efforts.
  • Prognosis remains poor, with only 32% recovery after exposure cessation and a 10-fold increase in symptoms with continued exposure.
  • Workers' compensation data reveal persistent underdiagnosis of WRA.

Conclusions:

  • Clinicians must maintain high suspicion for occupational causes of asthma in working adults.
  • Early diagnosis, exposure cessation, and workplace assessments are crucial for managing WRA.
  • Establishing the Korea Occupational Disease Surveillance Center presents an opportunity to improve WRA surveillance and address the diagnostic gap.