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Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
Published on: August 7, 2017
How Pregnancy Affects Asthma in Korea: Risk Factors and Adherence Decline.
Myoung-Nam Lim1, Jin-Sung Park2, Jae-Woo Kwon3,4
1Biomedical Research Institute, Kangwon National University Hospital, Chuncheon, Korea.
Allergy, Asthma & Immunology Research
|June 1, 2026
Summary
Maintaining long-term asthma control and medication adherence during pregnancy is crucial for preventing exacerbations. Postpartum management and patient education are vital for women with asthma.
Area of Science:
- Obstetrics and Gynecology
- Pulmonology
- Pharmacology
Background:
- Pregnancy significantly impacts asthma control, increasing exacerbation risk.
- Predicting asthma exacerbations during pregnancy remains challenging.
- Asthma management adherence during and after pregnancy requires further investigation.
Purpose of the Study:
- To evaluate pregnancy's impact on asthma control in Korean women.
- To identify risk factors for asthma exacerbations during pregnancy.
- To assess asthma medication adherence during and postpartum.
Main Methods:
- A case-control study utilized Korean National Health Insurance claims data (2012-2015).
- Asthma was defined by diagnoses and medication use within 4 years pre-conception.
- Exacerbations were identified by oral corticosteroid use, hospitalization, or ED visits.
Main Results:
- 14.8% of 123,355 women experienced exacerbations; 82.9% discontinued medication.
- Long-term asthma control (4 years pre-conception) predicted outcomes better than short-term.
- Poor adherence, pre-pregnancy exacerbations, rhinitis, multiple gestation, and neuropsychiatric disorders increased risk.
Conclusions:
- Sustained asthma control and medication adherence throughout pregnancy are critical.
- Comorbidities like rhinitis and neuropsychiatric disorders identify high-risk individuals.
- Continuous asthma management and education are essential before, during, and after pregnancy.
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