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Mapping Neuro Behcet's Disease Across North Africa: a Systematic Review and Meta Analysis
Nabil Belfeki1, Nouha Ghriss2, Monia Smiti3,4
1Department of Internal Medicine and Clinical Immunology, Groupe Hospitalier Sud Ile de France, Melun, France. nabil.belfeki@ghsif.fr.
Clinical Reviews in Allergy & Immunology
|June 1, 2026
Summary
Neuro-Behçet's disease affects 18.54% of Behçet's disease patients in North Africa, predominantly with parenchymal involvement. This systematic review highlights frequent neurological symptoms and supports clinical diagnosis over imaging alone.
Area of Science:
- Neurology
- Rheumatology
- Systematic Review & Meta-Analysis
Background:
- Limited data exists on neuro-Behçet's disease (NBD) in North Africa.
- Understanding NBD's frequency and characteristics in this region is crucial for patient management.
Conclusions:
- Neurological involvement is frequent in North African Behçet's disease patients, with a predominance of parenchymal forms.
- This meta-analysis provides a benchmark for North African NBD against global patterns.
- Integrated clinical diagnosis is supported over sole reliance on imaging.
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