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Endoscopic Management of Sinonasal Ossifying Fibroma: Clinical Experience From a Single Institution
Hyeong Seok Lee1, Dong Hoon Lee, Sang Chul Lim
1Department of Otolaryngology-Head and Neck Surgery, Chonnam National University Medical School and Hwasun Hospital, Hwasun, South Korea.
Background:
Sinonasal ossifying fibroma (OF) is a rare benign fibro-osseous tumor that can cause locally aggressive disease of the paranasal sinuses and skull base. Data on the outcomes after contemporary endoscopic management remain limited.
Methods:
We retrospectively reviewed patients with pathologically confirmed sinonasal OF diagnosed at a tertiary referral center. Seven patients were included in this study. Four patients who underwent definitive endoscopic endonasal surgery with complete resection and postoperative follow-up were included in the outcome analyses.
Results:
The lesions arose from the ethmoid sinus (n=2), maxillary sinus (n=1), and sphenoid sinus (n=1). All tumors had well-defined margins and a mixed-density pattern on computed tomography. All patients underwent endoscopic endonasal resection with complete excision. After a median follow-up of 24 months (range: 3-69 mo), no recurrence was observed, and none showed evidence of disease during the last follow-up.
Conclusion:
Complete endoscopic resection of the sinonasal OF achieved excellent short- to mid-term disease control without major morbidity.
