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Updated: Jun 3, 2026

Coculture Analysis of Extracellular Protein Interactions Affecting Insulin Secretion by Pancreatic Beta Cells
05:51

Coculture Analysis of Extracellular Protein Interactions Affecting Insulin Secretion by Pancreatic Beta Cells

Published on: June 15, 2013

Coordinated expression and assembly of BiP, p58IPK, and ER chaperone complexes maximize proinsulin folding in

Insook Jang1, Alec Duffey1, Pamela Itkin-Ansari1

  • 1Cancer Metabolism and Microenvironment Program, National Cancer Institute-Designated Cancer Center, Center for Metabolic and Liver Diseases, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA 92037.

Proceedings of the National Academy of Sciences of the United States of America
|June 1, 2026
PubMed

Keywords:
chaperonesendoplasmic reticulumproinsulin foldingtype 2 diabetesβ cell function

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