Investigation of Bioinspired Nanocurcumin Composites for Antibacterial Applications

Curcumin is the main curcuminoid present in turmeric (Curcuma longa). Various studies have shown that curcumin has excellent antimicrobial properties and enhances the wound healing process. Herein, this study we have made an attempt to synthesis and to explore the antibacterial efficacy of two different materials: curcumin reduced graphene oxide (C-rGO) and nano curcumin reduced graphene oxide composite (NC-rGO). These materials were further characterized, and their antibacterial potency was checked against Escherichia coli. According to microstructural characterization the C-rGO composite had a sheet-like uneven structure, whereas NC-rGO composite had spherical morphology. The presence of O-H group in both the composites was confirmed by Fourier transform infrared analysis. The zone of inhibition of C-rGO was 9.5 ± 0.47 mm whereas the zone of inhibition of NC-rGO was 11 ± 0.6 mm. These results indicate that NC-rGO might be used as an antibacterial agent in ointments and dressing bandages to prevent any secondary infection.