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Updated: Jun 3, 2026

Normothermic Machine Perfusion of Rat Kidneys for Transplantation
Published on: January 27, 2026
Kidney Container for Organ Perfusion Machines
Loraine C Goenaga-Mafud1, José D Vollet-Filho1, Daniel J Chianfrone1
1From the Sao Carlos Institute of Physics (IFSC), University of Sao Paulo (USP), Sao Carlos, São Paulo, Brazil.
Abstract:
The development of technologies in the field of organ transplantation is a highly relevant topic due to the significant impact these techniques have on improving the quality of life of patients with kidney diseases. This work presents the description of an invention designed to be used as a single-use, affordable product in hypothermic perfusion machines. The invention, named Renal Container, is a flexible polyvinyl chloride (PVC) receptacle, disposable, single-use, highly resistant, with an internal cradle designed to accommodate the kidney. The results of pilot experiments of hypothermic machine perfusion using the Renal Container showed good process performance over 4 hours of perfusion, with no visible histological alterations in the perfused renal tissues.
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