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Discovery of pyrazole-based selective covalent ITK inhibitors with In vivo activity

Zhiyang Ruan1, Zhengying Pan1

  • 1State Key Laboratory of Chemical Oncogenomics, Key Laboratory of Chemical Genomics, School of Chemical Biology and Biotechnology, Shenzhen Graduate School, Peking University, Shenzhen, 518055, China.

European Journal of Medicinal Chemistry
|June 1, 2026
PubMed
Abstract

Keywords:
Covalent inhibitorInterleukin-2 inducible T-cell kinaseSelectivity

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