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Mouse Models of Cancer Study02:43

Mouse Models of Cancer Study

Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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Mouse Models of Cancer Study02:43

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Mice have long served as models for studying human biology and pathology because of their phylogenetic and physiological similarity with humans. They are also easy to maintain and breed in the laboratory, and hence, many inbred strains are now available for research. Studies on mice have contributed immeasurably to our understanding of cancer biology.
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Cancer Prevention02:59

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Cancer Prevention02:59

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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
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Rous Sarcoma Virus (RSV) and Cancer01:03

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Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand  RNA genome. Its genome consists of four main open...

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  3. A European Collaborative Initiative To Systematically Map Cancer Risk By Migration Background: The Cancer Radar Project.
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  3. A European Collaborative Initiative To Systematically Map Cancer Risk By Migration Background: The Cancer Radar Project.

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Standardized SDS-PAGE Workflow for Personalized Protein Corona Profiling in Early Cancer Detection
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Published on: December 19, 2025

A European collaborative initiative to systematically map cancer risk by migration background: the Cancer RADAR

Catharina Johanna Alberts1,2,3, Damien Georges4, Freddie Bray5

  • 1Epidemiology of Data Science Department, Amsterdam UMC, Amsterdam, the Netherlands. c.j.alberts@amsterdamumc.nl.

International Journal for Equity in Health
|June 2, 2026

View abstract on PubMed

Summary
This summary is machine-generated.

Cancer RADAR establishes a framework for collecting comparable cancer data across Europe, stratified by migration background. This initiative aims to reduce cancer inequalities and inform data-driven health policies for migrant populations.

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Area of Science:

  • Public Health
  • Epidemiology
  • Health Services Research

Background:

  • The World Health Organization (WHO) emphasizes improved migration health governance and data-driven policies.
  • A significant barrier in Europe is the absence of consistent, comparable cancer data for individuals with a migration background.

Purpose of the Study:

  • To assess the availability of routine data for mapping and analyzing cancer risk differences among migrant populations in Europe.
  • To develop a framework for collecting cancer data stratified by country of birth for specific cancer types (breast, colorectal, cervical, stomach, liver, lung).

Main Methods:

  • Collaboration with pilot population-based cancer registries across Europe.
  • Development of a framework to collect cancer data stratified by country of birth.
  • Co-development of a protocol and analysis tool with pilot registries for data collection and protection (anonymization, aggregation).

    • Main Results:

    • High feasibility: 60% of registries are able and willing to share data, with an additional 10% intending to retrieve and share data from 22 countries.
    • Motivations for data sharing include reducing cancer inequalities and enhancing registry visibility.
    • Barriers identified include time constraints, resource limitations, and the need for ethical/legal approval, especially for data linkage.

    Conclusions:

    • Cancer RADAR offers a collaborative framework for systematic, comparable cancer data collection by migration background across Europe.
    • This framework is a crucial step towards standardized international comparisons.
    • The initiative supports evidence-based policies to effectively address cancer inequalities in migrant populations.