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Resting-State Connectivity and Neuroimaging of Prefrontal Cortex Activity During a Block-Design Yoga Asana Practice Using fNIRS
Published on: June 24, 2025
Somatic yoga therapy for functional neurological disorder: feasibility randomised controlled trial
Emily Kennedy-Barnes1, L S Merritt Millman1, Yasmine Basamh1
1Department of Psychological Medicine, https://ror.org/0220mzb33Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Background:
Functional neurological disorder (FND) is characterised by disabling motor, sensory and/or seizure symptoms. Contemporary models highlight the possible involvement of altered affective and autonomic regulation and interoceptive processing in FND. However, accessible, mechanism-informed interventions remain limited.
Aims:
This study sought to examine the feasibility, acceptability and possible benefits of tailored somatic yoga for people with FND, aiming to directly target altered emotional and bodily regulation in this group.
Method:
This single-site, two-arm randomised feasibility trial allocated adults with FND to 6 weeks of either somatic yoga (weekly remote sessions plus home practice manual) or a music-based relaxation control. Feasibility outcomes included recruitment, retention, adherence and acceptability. Secondary outcomes, assessed at baseline, week 3, week 6 and 3-month follow-up, included FND symptom burden, psychological symptoms (anxiety, depression, dissociation), general functioning, health-related quality-of-life, interoceptive awareness and autonomic symptoms.
Results:
Seventy-six enquiries were received. Thirty participants consented (100%), 27 were randomised (90%), 23 commenced the trial (77%) and 21 completed it (70%). Recruitment and retention targets were met, with 100% retention in the yoga arm. Adherence was high across both groups, although digital logging of home practice posed usability challenges. Exploratory analyses indicated large effect sizes for self-reported FND symptom improvement and interoceptive awareness in the yoga group, with effects sustained at follow-up.
Conclusions:
Individually delivered somatic yoga was found to be feasible, acceptable and safe for people with FND. Our results also suggest potential benefits of somatic yoga for FND symptom improvement and interoceptive awareness, supporting progression to a fully powered trial.
