Related Experiment Video
Updated: Jun 3, 2026

Generation of a Mouse Spontaneous Autoimmune Thyroiditis Model
Published on: March 17, 2023
A Case Report of a Patient with Thyroid eye disease Induced by Hashimoto's Thyroiditis
M H Khaskhazyan1, D K Shaghbatyan2, T A Ambartsumyan3
1Medline clinic and National Institute of Health Named After Academician S. Avdalbekyan.
Background:
Autoimmune thyroid diseases (AITD) result from immune system dysregulation. Among them are Hashimoto's thyroiditis, Graves' disease, etc. Approximately 3% of patients with Hashimoto's thyroiditis may develop orbitopathy. Thyroid eye disease (TED), is an organ-specific autoimmune reaction that primarily affects the eyes and surrounding tissues. The aim of this case report is to present a rare condition of a female patient who was diagnosed with exophthalmos nine years after being diagnosed with Hashimoto's thyroiditis.
Case Report:
A 45-year-old woman presented to our department with Hashimoto's thyroiditis and hypothyroidism. Her medical history revealed that she was diagnosed with HT nine years ago and had been receiving L-thyroxine treatment throughout this period. However, her condition remained uncompensated, and in the past year, she developed bilateral exophthalmos as a complication.
Conclusion:
Exophthalmos is generally more strongly associated with Graves' disease, a form of hyperthyroidism. However, it can also occur in some patients with Hashimoto's thyroiditis, although it is less common.
Related Concept Videos
Graves' Disease I: Introduction
Graves Disease II: Pathophysiology
Hyperthyroidism I: Introduction
Hyperthyroidism II: Pathophysiology
Hypothyroidism II: Pathophysiology
Goiter
