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Updated: Jun 3, 2026

Important Endpoints and Proliferative Markers to Assess Small Intestinal Injury and Adaptation using a Mouse Model of Chemotherapy-Induced Mucositis

Important Endpoints and Proliferative Markers to Assess Small Intestinal Injury and Adaptation using a Mouse Model of Chemotherapy-Induced Mucositis

Published on: May 12, 2019

[Research on 5-Fluorouracil-Induced Injury in Human Intestinal Organoids].

Jia-Rui Fang^1,2, Xiao-Tong Li², Heng Zhu²

¹Mudanjiang Medical University, Mudanjiang, Heilongjiang 157011, China.

Zhongguo Shi Yan Xue Ye Xue Za Zhi

|June 2, 2026

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Protein Microarrays and Liposome: A Method for Studying Lipid-Protein Interactions.

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5-fluorouracil (5-FU) damages human intestinal organoids (HIOs) by destroying structure and increasing inflammation. This study establishes a model for investigating 5-FU

Area of Science:

Stem cell biology and regenerative medicine
Gastroenterology and oncology
Pharmacology and toxicology

Keywords:

human induced pluripotent stem cells; human intestinal organoids; 5-fluorouracil; inflammatory response

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