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Updated: Jun 3, 2026

Transtubular Endoscopic Posterolateral Decompression for L5-S1 Lumbar Lateral Disc Herniation
Published on: October 14, 2022
A Comprehensive Assessment of Clinical, Radiological, and Histopathological Parameters in Lumbar Disc Herniation
Aim:
To provide deeper insights into the biological mechanisms underlying disc degeneration and recurrence by studying histopathological features of excised disc tissue. Moreover, due to limited predictive role of radiological grading systems like Pfirrmann and Modic classifications in understanding postoperative outcomes and recurrence mechanisms, to perform holistic analysis on clinical, patient specific factors, radiological and histological findings on matrix correlation statistics.
Material And Methods:
We conducted a retrospective study including 87 patients who underwent lumbar discectomy between 2019 and 2024. Detailed preoperative magnetic resonance imaging (MRI) evaluations using Pfirrmann grading, along with semi-quantitative histopathological analysis, were performed. Statistical analyses included Spearman correlation and ANOVA to explore relationships between clinical, radiological, and histopathological parameters.
Results:
Higher Pfirrmann grades were significantly associated with radiological instability (p.
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