Cancerous Arrhythmia: Metastatic Cervical Cancer to the Heart Complicated by Ventricular Tachycardia
Sarah Noorani1, Kevin S Tang2, Akash Patel3
1Department of Medicine, University of California-Irvine Medical Center, Orange, California, USA.
Background:
Cardiac metastasis from cervical cancer presenting with ventricular arrhythmias is an exceedingly rare phenomenon that requires a multidisciplinary approach for management and prognostication.
Case Summary:
A woman with cervical squamous cell carcinoma presented with nonsustained ventricular tachycardia. Imaging revealed a 4-cm right ventricular mass with biopsy consistent with metastatic cervical squamous cell carcinoma. The patient was a poor surgical candidate and was managed with chemotherapy and ambulatory cardiac monitoring with close outpatient follow-up.
Discussion:
Cardiac metastasis is a rare occurrence that requires consideration of surgical candidacy, appropriate cytotoxic therapy, and management of complications. Ventricular arrhythmias are infrequently described but should be first managed with antiarrhythmic drugs, although sparse reports exist of radiofrequency ablation.
Take-Home Messages:
Dangerous ventricular arrhythmias are a rarely described complication of cardiac metastasis from cervical cancer. Optimal management is poorly defined but should involve a multidisciplinary approach and consideration of both surgical and medical therapies.
Related Concept Videos
Dysrhythmias II: Classification of Tachyarrhythmias
Mechanism of Cardiac Arrhythmias
Dysrhythmias III: Characteristics of Dysrhythmias
Disturbances in Heart Rhythm
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
ECG Interpretation of Arrhythmias I: Sinus Arrhythmias
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism, and...

