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Updated: Jun 4, 2026

Semi-High Throughput Screening for Potential Drought-tolerance in Lettuce (Lactuca sativa) Germplasm Collections
Published on: April 17, 2015
The Lettuce Expression Browser: from lab to LEB
Dirk-Jan M van Workum1, Esther S van den Bergh2, Siddhant S Shetty3
1Bioinformatics Group, Wageningen University and Research, Droevendaalsesteeg 1, 6708 PB, Wageningen, The Netherlands.
We created the Lettuce Expression Browser (LEB), a new tool mapping gene activity across lettuce tissues and conditions. This resource aids research into lettuce development, stress responses, and crop improvement.
Area of Science:
- Plant science
- Genomics
- Bioinformatics
Background:
- Lettuce (Lactuca sativa L.) is a key crop with growing genomic resources.
- Existing gene expression data lacks tissue-specific resolution and clear visualization.
- This limits functional genomics studies in the Asteraceae family.
Purpose of the Study:
- To develop a high-resolution gene expression resource for lettuce.
- To provide an intuitive platform for exploring gene activity across tissues and conditions.
- To support research in lettuce development, stress responses, and crop improvement.
Main Methods:
- Developed the Lettuce Expression Browser (LEB) platform.
- Integrated transcriptomic data from diverse lettuce tissues, developmental stages, and abiotic stress treatments (salt, far-red).
- Visualized expression data using the ggPlantmap R package.
Main Results:
- Created comprehensive, high-resolution gene expression maps for cultivated and wild lettuce species.
- The LEB platform offers an intuitive interface for exploring gene expression patterns.
- The resource visualizes expression across organs, tissues, and developmental stages.
Conclusions:
- The Lettuce Expression Browser (LEB) is a valuable public resource for lettuce functional genomics.
- It enhances understanding of lettuce development, abiotic stress responses, and evolutionary genomics.
- LEB will facilitate lettuce research and crop improvement efforts.
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