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The Five Essential Concepts of Developmental Medicine: A Medical Paradigm for People with Developmental Disabilities

Ryan Daniel1, Bronwyn Bennett1, Linda Edwards1

  • 1University of Florida College of Medicine - Jacksonville, Jacksonville.

Southern Medical Journal
|June 2, 2026
PubMed

Insights

A new clinical model, the "Five Essential Concepts of Developmental Medicine," guides adult care for neurodevelopmental disorders (NDDs). It ensures comprehensive management and improves quality of life for individuals with developmental disabilities.

Area of Science:

  • Developmental Medicine
  • Neurodevelopmental Disorders
  • Adult Health Care

Background:

  • Lifelong neurodevelopmental disorders (NDDs) pose complex health challenges, especially during the transition from pediatric to adult care.
  • Symptoms of NDDs, including cognitive, motor, seizure, and behavioral issues, vary significantly among individuals.
  • Existing healthcare systems often struggle to provide comprehensive and continuous care for adults with NDDs.

Purpose of the Study:

  • Introduce a structured clinical model, the "Five Essential Concepts of Developmental Medicine," for managing adults with NDDs.
  • Provide a framework to guide healthcare professionals in delivering individualized and comprehensive care.
  • Address the gap in healthcare for adults with NDDs and developmental disabilities.

Main Methods:

  • The proposed model outlines five key areas: understanding childhood-onset brain dysfunction, specific neurodevelopmental diagnosis, complication recognition, secondary consequence assessment, and syndrome-specific condition management.
  • Emphasizes individualized care planning to prevent diagnostic overshadowing.
  • Advocates for integrated, multidisciplinary care systems with tailored screenings and proactive management.

Main Results:

  • The model offers a structured approach to prevent diagnostic overshadowing.
  • Promotes comprehensive health management by addressing unique medical needs.
  • Facilitates tailored screenings, early diagnosis, and proactive interventions.

Conclusions:

  • The "Five Essential Concepts of Developmental Medicine" model provides a vital framework for improving the care of adults with NDDs.
  • Integrated, multidisciplinary care is crucial for addressing the complex needs of this population.
  • This approach aims to enhance the quality of life and ensure equitable healthcare access for individuals with developmental disabilities throughout their lifespan.

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