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Inflammation-driven transcriptional reprogramming in prostate cancer: Convergence of NFκB, JAK/STAT3, and epigenetic

Madhu Krishna1, Pankaj Garg2, David Horne3

  • 1Department of Medical Oncology and Therapeutic Research, Beckman Research Institute, City of Hope Comprehensive Cancer Center and National Medical Center, 1500 E Duarte Road, Duarte, CA, 91010, USA.

Cancer Letters
|June 2, 2026
PubMed

Keywords:
Androgen receptor (AR)Castration-resistant prostate cancer (CRPC)Epigenetic remodelingInterleukin-6 (IL6)Janus kinase/signal transducer and activator of transcription 3 (JAK/STAT3)Nuclear factor kappa B (NFκB)Prostate cancer (CaP)

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