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GPSM2 Promotes Pancreatic Cancer Progression Through METTL3-Mediated m6A Modification of YAP1 mRNA

Jiajun Xiu1,2, Li Qiao2, Miaomiao Li3

  • 1Oujiang Laboratory (Zhejiang Lab for Regenerative Medicine, Vision and Brain Health), Wenzhou Medical University, Wenzhou, Zhejiang, China.

Journal of Cellular and Molecular Medicine
|June 2, 2026
PubMed
Summary

G-protein signalling modulator 2 (GPSM2) promotes pancreatic cancer growth by stabilizing Yes-associated protein 1 (YAP1) mRNA. This discovery offers new therapeutic targets for pancreatic cancer intervention.

Keywords:
GPSM2IGF2BP2/3METTL3YAP1m6Apancreatic cancer

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