The Present and Future of THERANOSTICS

Area of Science:

• Nuclear medicine
• Oncology
• Radiopharmaceutical therapy

Background:

• Growing global interest in radiotheranostics for precision cancer medicine.
• Radiotheranostics offer targeted detection and treatment of cancer.

Purpose of the Study:

• Review current developments in radiopharmaceutical therapy.
• Discuss approved agents, late-stage clinical trials, and emerging radionuclides/targets.
• Examine operational, regulatory, and regional challenges, including in East and Southeast Asia.

Main Methods:

• Literature review of radiopharmaceutical developments.
• Analysis of approved radiopharmaceuticals and agents in clinical trials.
• Discussion of novel ligands, targets, and therapeutic combinations.

Main Results:

• Overview of approved radiopharmaceuticals and those in late-stage trials.
• Identification of emerging radionuclides and cancer targets.
• Exploration of challenges in radiopharmaceutical therapy implementation.

Conclusions:

• Radiotheranostics represent a significant advancement in precision oncology.
• Continued research and development are crucial for expanding radiopharmaceutical applications.
• Addressing regulatory and operational hurdles is key for wider adoption, especially in diverse Asian healthcare systems.