Recurrent Candida parapsilosis Complex Endocarditis in a Patient With a Mechanical Mitral Prosthetic Valve Managed...

Infective endocarditis is an infection of the endocardium and cardiac valves. Fungal etiologies are rare, accounting for 1-3% of cases, and affect prosthetic valves in 0.1% of cases. We present a case of recurrent fungal endocarditis, caused by Candida parapsilosis in a patient with a mechanical mitral prosthetic valve successfully managed with medical therapy alone in a resource-limited setting. This report highlights the diagnostic and therapeutic challenges of fungal endocarditis and demonstrates that under appropriate clinical conditions, such as the absence of congestive heart failure, heart block, thrombotic events, and close monitoring with appropriate antifungal therapy, favorable outcomes may be achieved even in the absence of surgical intervention.