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Knowledge and Preventive Practices Regarding Nonsteroidal Anti-inflammatory Drug (NSAID)-Induced Kidney Injury Among
Yahia Atef Albashtawi1, Zaina Rawashdeh2, Jihan B Jerjeous2
1Urology, Abdali Hospital, Amman, JOR.
Cureus
|June 3, 2026
Summary
Improving knowledge about nonsteroidal anti-inflammatory drug (NSAID)-induced kidney injury is linked to safer practices among chronic users. Targeted education on risks like asymptomatic injury and hydration is recommended to prevent kidney harm.
Area of Science:
- Pharmacology
- Nephrology
- Public Health
Background:
- Nonsteroidal anti-inflammatory drugs (NSAIDs) are common pain relievers.
- Inappropriate NSAID use is a known cause of kidney injury.
- Understanding of NSAID risks and prevention among chronic users is limited.
Purpose of the Study:
- To assess knowledge and preventive practices concerning NSAID-induced kidney injury in chronic NSAID users.
- To investigate the relationship between knowledge and preventive practices.
Main Methods:
- A cross-sectional study utilized an anonymous online survey distributed via social media.
- 300 adult chronic pain patients using NSAIDs regularly participated.
- Knowledge and preventive practice scores were calculated and analyzed for association.
Main Results:
- Mean knowledge score was 3.97/6 and mean practice score was 8.54/12.
- Low awareness of asymptomatic kidney injury and inconsistent practices like reading leaflets and avoiding NSAIDs during dehydration were noted.
- A significant positive association (τ = 0.317, p < 0.001) was found between knowledge and practice scores.
Conclusions:
- Enhanced knowledge correlates with safer NSAID use.
- Educational interventions focusing on asymptomatic injury, hydration, and medication leaflets are crucial.
- Pharmacist-led counseling can mitigate NSAID-related renal harm.
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