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Updated: Jun 4, 2026
External Cephalic Version: Is it an Effective and Safe Procedure?
Published on: June 6, 2020
Efficacy and cost-effectiveness of intraoperative cell salvage for patients with placenta previa during cesarean
Le Zhang1, Yaojun Lu1, Hanli Hua1
1Department of Anesthesiology, Obstetrics and Gynecology, Hospital of Fudan University, Shanghai Key Lab of Reproduction and Development, Shanghai Key Lab of Female Reproductive Endocrine Related Diseases, Shanghai, China.
Objectives:
This study aimed to evaluate whether intraoperative cell salvage (ICS) and retransfusion reduce allogeneic blood transfusion (ABT) requirement and treatment costs in patients with placenta previa undergoing cesarean section.
Methods:
We retrospectively enrolled 102 pregnant women who underwent ICS and 113 women who did not. The primary outcomes included ABT rate, ABT volume, routine blood tests, and coagulation function before and 24 h after surgery. Secondary outcomes included the costs of all blood component transfusions. Linear regression analysis was performed to identify independent risk factors for ABT.
Results:
No statistically significant difference in ABT rate was found between the ICS and control groups. Linear regression analysis revealed that estimated blood loss (EBL) and operative time were independent risk factors for ABT. Subgroup analysis showed that the overall ABT rate, median ABT volume and median RBC values were significantly different between the ICS group and the control group for patients with EBL <800 mL; in patients with EBL >800 mL, the median RBC transfusion was significantly lower in the ICS group. The median ABT cost was significantly higher in the ICS group than in the control group in patients with EBL <800 mL and operative time <67 min, but no significant difference was observed in other subgroups. Postoperatively, the median hemoglobin and hematocrit levels were significantly higher in the ICS group than in the control group.
Conclusions:
ICS may be recommended for placenta previa patients who undergo cesarean section for more than 1 h.
