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Case Report: Cervical lymphadenitis resulting from Pseudomonas aeruginosa diagnosed by metagenomic next-generation
Lihong Gao1,2, Yang Wen2,3, Xiaoyu Jing2,4
1Department of Pediatric Infectious Diseases Nursing Unit, West China Second University Hospital, Sichuan University, Chengdu, Sichuan, China.
Insights
Pediatric cervical lymphadenitis, often caused by common bacteria, can rarely stem from Gram-negative pathogens like Pseudomonas aeruginosa. Metagenomics next-generation sequencing aided in diagnosing this rare case, enabling effective treatment.
Area of Science:
- Pediatric infectious diseases
- Microbiology
- Genomics
Background:
- Pediatric cervical lymphadenitis is typically caused by Staphylococcus aureus and Streptococcus pyogenes.
- Infections due to Gram-negative bacteria are uncommon in pediatric cervical lymphadenitis.
Abstract:
Pediatric cervical lymphadenitis is usually caused by Staphylococcus aureus and Streptococcus pyogenes. Cases resulting from Gram-negative bacteria are rare. Herein, we report the case of an 11-year-old boy who developed cervical lymphadenitis. He was diagnosed with a Pseudomonas aeruginosa infection through metagenomics next-generation sequencing of blood and biopsy. After treatment with meropenem, the patient's condition improved and he was discharged. Lymphadenitis may be caused by Gram-negative opportunistic pathogens. Metagenomic next-generation sequencing can help identify the underlying cause.
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