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Updated: Jun 4, 2026

Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
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The interplay of complex PTSD, intimate partner violence, and metacognitive beliefs in driving methamphetamine

Roya Forootan1, Shahram Mohammadkhani1, Mehdi Akbari1

  • 1Department of Clinical Psychology, Faculty of Psychology and Education, Kharazmi University, Tehran, Iran.

Addictive Behaviors Reports
|June 3, 2026
PubMed
Summary
This summary is machine-generated.

Complex post-traumatic stress disorder and intimate partner violence directly impact craving in women with methamphetamine use disorder. Metacognitive beliefs about desire thinking mediate this relationship, highlighting targets for intervention.

Keywords:
Complex post-traumatic stress disorderCravingIntimate partner violenceMetacognitive beliefsMethamphetamine use disorderPerceived social support

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Area of Science:

  • Psychology
  • Clinical Psychology
  • Addiction Research

Background:

  • Craving is a key factor in relapse for substance use disorders (SUDs), especially in women.
  • Complex post-traumatic stress disorder (CPTSD) and intimate partner violence (IPV) are prevalent among women with SUDs and may influence craving.

Purpose of the Study:

  • To investigate the direct associations of CPTSD and IPV with craving in women with methamphetamine use disorder.
  • To examine the mediating roles of perceived social support and metacognitive beliefs about desire thinking in these relationships.

Main Methods:

  • Structural equation modeling was used to analyze data from 244 women diagnosed with methamphetamine use disorder.
  • Participants were recruited from addiction treatment centers in Iran.

Main Results:

  • Both CPTSD and IPV were directly associated with increased craving.
  • Metacognitive beliefs about desire thinking significantly mediated the relationship between CPTSD/IPV and craving.
  • Perceived social support did not emerge as a significant mediator.

Conclusions:

  • Trauma-related psychopathology (CPTSD) and intimate partner violence significantly contribute to craving in women with methamphetamine use disorder.
  • Maladaptive metacognitive processes related to desire thinking are crucial targets for interventions.
  • Findings support the development of trauma-informed and metacognitive-focused treatments for this population.