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Updated: Jun 4, 2026

Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
Mastering the maze: navigating prolonged air leak in thoracic surgery
Clarissa Uslenghi1, Luca Bertolaccini1, Monica Casiraghi1,2
1Department of Thoracic Surgery, IEO, European Institute of Oncology IRCCS, Milan, Italy.
Prolonged air leak (PAL) after thoracic surgery, often an alveolar-pleural fistula (APF), complicates recovery. Strategies include intraoperative detection, digital chest drains, and interventions like autologous blood patching to improve patient outcomes.
Area of Science:
- Thoracic Surgery
- Pulmonary Medicine
- Surgical Complications
Background:
- Prolonged air leak (PAL) is a significant complication in thoracic surgery, leading to alveolar-pleural fistula (APF).
- Risk factors include smoking and specific surgical techniques like segmentectomies, necessitating preoperative assessment.
- PAL negatively impacts patient recovery, quality of life, and increases healthcare costs.
Purpose of the Study:
- To review current challenges and strategies for managing prolonged air leak (PAL) in thoracic surgery.
- To highlight the impact of PAL on patient outcomes and healthcare expenditure.
- To discuss advancements in PAL detection and management, particularly in visualised thoracic surgery.
Main Methods:
- Review of existing literature on prolonged air leak (PAL) in thoracic surgery.
- Analysis of intraoperative techniques for PAL detection and management, including submersion tests and near-infrared fluorescence imaging.
- Evaluation of postoperative management strategies, chest drainage systems, and long-term interventions such as autologous blood patching.
Main Results:
- Standardizing intraoperative management through consensus initiatives and employing aerostatic interventions show promise in reducing PAL incidence.
- Digital chest drains offer enhanced monitoring and precision in postoperative management.
- Autologous blood patching is identified as a cost-effective intervention for long-term PAL management.
Conclusions:
- Addressing PAL requires a comprehensive, individualized approach due to its multifactorial nature.
- Visualised thoracic surgery techniques, while beneficial, still face challenges with PAL, necessitating advanced intraoperative management.
- Continued research and collaborative efforts are crucial for optimizing patient outcomes and reducing healthcare costs associated with PAL.
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