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Updated: Jun 4, 2026

Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Pd-Catalyzed Vinylic C-H Funtionalization for the Synthesis of 1,4-Disilylated 1,3-Dienes
Xiaoyu Qiu1, Dongsheng Yi1, Xiang Zuo1
1School of Chemical Science and Engineering, Tongji University, Shanghai 200092, China.
Abstract:
A palladium-catalyzed C-H silylation reaction of alkenyl triflates has been developed, employing a norbornene analogue as a relay for C-H activation. The reaction forms C(vinyl), C(alkyl)-palladacycles as the key intermediates via norbornene analogue-relayed C-H activation. These palladacycles subsequently react with a disilane to form disilylated intermediates, which undergo a retro-Diels-Alder reaction to deliver the final products. This method offers an efficient route to Z,Z-1,4-disilylated 1,3-dienes.
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