Highlight of 2025: From binding prediction to molecular design-computational advances in TCR-pMHC prediction and
Kilian J Maire1, Jonathan M Coquet1
1LEO Foundation Skin Immunology Research Centre, Dept. Immunology and Microbiology (ISIM), University of Copenhagen, Copenhagen, Denmark.
Immunology and Cell Biology
|June 3, 2026
Abstract:
In this article, we highlight recent progress in the field of TCR-peptide-MHC prediction and outline remaining gaps in prediction power. We also touch on exciting advancements in molecular design that allow for precise targeting of peptide-MHC complexes.
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