The effect of pulse frequency and amplitude on hemodynamics in the carotid artery bifurcation
Mudrika Singhal1, Mahesh S Nagargoje1,2, Raghvendra Gupta1,3
1Department of Chemical Engineering, Indian Institute of Technology Guwahati, Assam, India.
Abstract:
This study computationally investigates hemodynamics in carotid artery bifurcation, examining the distinct effects of pulse rate and amplitude on blood flow. Using a shear-thinning fluid model with resistance boundary condition, three pulse rates and amplitudes are investigated. Results show that higher frequency and amplitude reduce reverse flow near the bifurcation, increasing time-averaged wall shear stress (TAWSS) while decreasing oscillatory shear index (OSI) and relative residence time (RRT). These hemodynamic changes are associated with reduced risk of atherosclerosis, suggesting that elevated heart rate and amplitude might play an atheroprotective role.
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