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GLP-1 Receptor Agonist Exposure and Malignancy Risk in Patients With Endogenous Cushing's Syndrome.

Idit Dotan1,2, Tzipora Shochat3, Shiri Kushnir4

  • 1Institute of Endocrinology, Beilinson Hospital, Rabin Medical Center, Petah Tikva, Israel.

The Journal of Clinical Endocrinology and Metabolism
|June 3, 2026
PubMed
Summary

Glucagon-like peptide-1 receptor agonists (GLP-1RAs) do not increase cancer risk in patients with Cushing's syndrome (CS), a population with a known higher risk of malignancy. This study found no association between GLP-1RA use and incident cancer in CS patients.

Keywords:
AdrenalCancerCushing’s diseaseCushing’s syndromeGLP

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