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Related Experiment Video

Updated: Jun 4, 2026

Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way
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Intraoperative Assessment of Resection Margins in Oral Cavity Cancer: This is the Way

Published on: May 10, 2021

Patient Satisfaction With Second-Intention Healing in Mohs Micrographic Surgery: A Systematic Review.

Chase A Pitchford1, Christian E Hemmerich2, Andrew S Desrosiers3

  • 1Department of Dermatology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|June 3, 2026
PubMed
Summary

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Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

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Second-intention healing (SIH) in Mohs micrographic surgery (MMS) provides high patient satisfaction and good cosmetic outcomes. Further research is needed to standardize patient-reported outcome measures for better decision-making.

Area of Science:

  • Dermatologic surgery
  • Reconstructive surgery
  • Patient-reported outcomes

Background:

  • Second-intention healing (SIH) is a traditional method for defect closure in Mohs micrographic surgery (MMS).
  • Reconstructive techniques have decreased SIH use, despite its proven efficacy in selected cases.
  • Patient perspectives on SIH are less understood compared to physician-reported outcomes.

Purpose of the Study:

  • To systematically review patient satisfaction and outcomes following SIH in MMS.
  • To synthesize existing literature on patient experiences with SIH after Mohs surgery.

Main Methods:

  • Systematic literature search conducted using PubMed and EMBASE.
  • Included studies assessing patient satisfaction, cosmetic, healing, and functional results of SIH post-MMS.

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  • Data extraction and quality assessment performed by two independent reviewers.

    • Main Results:

    • Eight studies met inclusion criteria, indicating high patient satisfaction with SIH.
    • Favorable cosmetic and functional outcomes were reported, with minor complications not significantly impacting satisfaction.
    • Variability in outcome assessment methods, including non-validated scoring systems, limits cross-study comparability.

    Conclusions:

    • Second-intention healing remains a viable reconstructive option in MMS for suitable patients.
    • High patient satisfaction is achievable with SIH in select cases.
    • Standardization of patient-reported outcome measures is crucial for improved comparability and decision-making in dermatologic surgery.