Related Experiment Video
Updated: Jun 4, 2026

The Flexible Rhino-Laryngoscope for Awake Nasotracheal Intubation
Published on: August 2, 2024
Flexible Intubation Scope versus Flexible Intubation Scope and Video Laryngoscopy Combination: A Prospective
Uduak Ursula Williams1, Pascal Owusu-Agyemang1, Catherine N Vu1
1From the Department of Anesthesiology and Perioperative Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Adding video laryngoscopy (VL) to a flexible intubation scope (FIS) did not significantly decrease difficult endotracheal tube (ETT) placement in patients with anticipated difficult airways. However, the combined FIS/VL approach improved first-pass success rates and reduced provider-rated difficult intubations.
Area of Science:
- Anesthesiology
- Airway Management
- Medical Devices
Background:
- Suboptimal airway management in patients with anticipated difficult airways can lead to increased perioperative morbidity and mortality.
- Combining video laryngoscopy (VL) with a flexible intubation scope (FIS) may improve visualization and endotracheal tube (ETT) passage.
- Limited randomized evidence currently supports the combined FIS/VL approach for difficult airways.
Purpose of the Study:
- To evaluate the effectiveness of a combined flexible intubation scope with video laryngoscopy (FIS/VL) compared to flexible intubation scope (FIS) alone for endotracheal intubation in adults with anticipated difficult airways.
- To assess the composite rate of difficult ETT placement, including intubation time, first-attempt failure, and provider-rated difficulty.
- To analyze secondary outcomes such as total intubation time and provider-rated ease of intubation.
Main Methods:
- A prospective, randomized trial involving 135 adult patients with anticipated difficult airways undergoing elective surgery.
- Patients were randomized 1:1 to intubation with either FIS alone or the combined FIS/VL technique.
- The primary endpoint was the composite rate of difficult ETT placement; secondary outcomes included total intubation time and provider-rated ease of intubation.
Main Results:
- The first-pass success rate was significantly higher in the FIS/VL group (93.1%) compared to the FIS group (78.1%) (P = .020).
- Provider-rated difficult or unsuccessful intubations were less frequent with FIS/VL (6.1%) versus FIS (19.4%) (P = .025).
- The composite primary endpoint of difficult ETT placement did not significantly differ between the groups (45.9% for FIS/VL vs. 59.7% for FIS; P = .118).
Conclusions:
- In adults with anticipated difficult airways, the addition of VL to FIS did not significantly reduce the composite rate of difficult endotracheal tube placement.
- The combined FIS/VL technique was associated with improved first-pass success rates and fewer provider-rated difficult/unsuccessful intubations.
- Dual-visualization strategies show clinical value for improving first-pass performance, but larger trials are needed to confirm effects on composite difficulty endpoints.
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