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Updated: Jun 4, 2026

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
10:52

Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence

Published on: December 23, 2022

Myocardial Infarction With Normal Coronary Arteries in 2 Patients With Patent Foramen Ovale

Eustaquio M Onorato1, Luca Grancini1, Francesco Casilli2

  • 1University Cardiology Department, I.R.C.C.S. Ospedale Galeazzi-Sant'Ambrogio, Milan, Italy.

JACC. Case Reports
|June 3, 2026
PubMed
Abstract

Insights

Paradoxical coronary artery embolism (PCAE) can cause acute coronary events in young adults. A patent foramen ovale (PFO) may be the underlying cause in patients with normal coronary arteries.

Area of Science:

  • Cardiology
  • Vascular Medicine
  • Pathophysiology

Background:

  • Paradoxical coronary artery embolism (PCAE) accounts for a significant portion of acute coronary events in individuals under 35.
  • Patent foramen ovale (PFO) is a potential, often overlooked, cause of PCAE.
Keywords:
migraine with auramyocardial infarction with nonobstructive coronary arteriesparadoxical coronary embolismpatent foramen ovaleright-to-left shunt

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