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Updated: Jun 4, 2026

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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
Patronus: patient-specific training setup for aortic aneurysm repair
Henry John Krumb1, Bernhard Dorweiler2, Anirban Mukhopadhyay3
1Computer Science Department, TU Darmstadt, Fraunhoferstr. 5, Darmstadt, 64293, Hessen, Germany. henry_john.krumb@tu-darmstadt.de.
Summary
PATRONUS is a novel simulator for radiation-free endovascular aneurysm repair (EVAR) training. It uses patient-specific 3D-printed phantoms and generates pseudo X-rays for realistic surgical simulation.
Area of Science:
- Medical Simulation
- Biomedical Engineering
- Radiology
Background:
- Endovascular Aneurysm Repair (EVAR) training typically involves X-ray guidance, posing radiation risks to patients and staff.
- Patient-specific phantoms enhance simulator realism but often lack realistic imaging capabilities in radiation-free setups.
- Current 3D-printed vascular models for training require advanced imaging techniques for accurate representation.
Purpose of the Study:
- To develop PATRONUS, a prototype for patient-specific, radiation-free surgical training for EVAR.
- To integrate 3D printing and advanced imaging for realistic simulation of endovascular procedures.
- To reduce radiation exposure during surgical training for EVAR.
Main Methods:
- PATRONUS utilizes 3D-printed, transparent phantoms within a controlled imaging environment.
- Pseudo X-rays are generated via reconstructed radiographs, enhanced with virtual catheters and contrast agents.
- A complete pipeline includes 3D printing, phantom preparation, and online registration to patient CT data.
Main Results:
- The prototype successfully demonstrates a full pipeline for radiation-free EVAR simulation.
- An average registration error of 9.30 mm was achieved between the phantom and its digital twin.
- The simulator pipeline processes images at a rate of 1.059 seconds per image.
Conclusions:
- Advanced 3D printing and scene understanding enable realistic digital twin representations of vascular phantoms.
- The PATRONUS simulator facilitates a transition towards radiation-free endovascular surgical training.
- This prototype lays the groundwork for enhanced, patient-specific training in EVAR procedures.
