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The Effect of Tribulus Terrestris on Acute Kidney Injury: A Case Study
Mahboobeh Freidoon1, Zahra Pourvali-Souraki2, Kimia Karimi Toudeshki3
1Assistant Professor, Department of Nephrology, Shohada-e-Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iranian Journal of Kidney Diseases
|June 3, 2026
Summary
Herbal medicine use, like Tribulus terrestris, can lead to serious kidney damage requiring dialysis. This case highlights the importance of medical guidance for herbal supplements to prevent adverse effects.
Area of Science:
- Herbal Medicine
- Nephrology
- Toxicology
Background:
- Herbal medications are popular among healthy individuals.
- Despite perceived safety, adverse effects from herbal products are reported.
- Tribulus terrestris is a commonly used herbal supplement.
Purpose of the Study:
- To raise awareness of potential toxicities associated with over-the-counter herbal medicines.
- To document a case of severe adverse event linked to herbal medicine use.
Main Methods:
- Case report of a 43-year-old male patient.
- Investigation of elevated creatinine levels.
- Clinical management and follow-up.
Main Results:
- The patient required dialysis due to elevated creatinine levels.
- The patient recovered after medical management.
- The patient remained asymptomatic at three months post-treatment.
Conclusions:
- Self-administration of herbal medicines can pose significant health risks.
- Medical supervision is crucial when using herbal supplements.
- Increased awareness of herbal medicine toxicity is needed.
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