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Updated: Jun 5, 2026

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis
04:36

Measurement of Tissue Oxygenation Using Near-Infrared Spectroscopy in Patients Undergoing Hemodialysis

Published on: October 2, 2020

Predictors of Survival and Clinical Outcomes in Hemodialysis Patients: A 9-Year Multicenter Cohort Study

Tayebeh Soleymanian1, Atefeh Yousefi2, Farnaz Tavakoli3

  • 11Professor of Nephrology, Nephrology and Kidney Transplantation Ward, Department of Internal Medicine, Shariati Hospital, School of Medicine, Tehran University of Medical sciences, Tehran, Iran.

Iranian Journal of Kidney Diseases
|June 3, 2026
PubMed

Insights

High mortality persists in hemodialysis patients. Older age, diabetes, and poor nutrition significantly increase mortality risk, highlighting the need for targeted interventions in end-stage kidney disease management.

Area of Science:

  • Nephrology
  • Internal Medicine
  • Public Health

Background:

  • Hemodialysis patients face high cardiovascular and non-cardiovascular mortality rates.
  • Despite advancements in dialysis, prognosis remains poor for many with end-stage kidney disease (ESKD).

Purpose of the Study:

  • To identify key factors associated with long-term mortality in adult hemodialysis patients.
  • To analyze causes of death and predict mortality risk in this vulnerable population.

Main Methods:

  • Prospective cohort study of 185 adult ESKD patients on maintenance hemodialysis.
  • Follow-up for 103 months (8.5 years) to track mortality and dialysis exit.
  • Cox proportional hazards model used for mortality prediction, adjusting for clinical and laboratory variables.

Main Results:

  • The cohort had a mean age of 57 years; 52.5% were male, and 48% had diabetes.
  • Mortality rate was 19 per 100 patient-years, with 71% of patients dying during the study.
  • Leading causes of death were cardiovascular diseases (47%) and infections (32.5%).

Conclusions:

  • Older age, diabetes mellitus, and poor nutritional biomarkers are significant predictors of mortality.
  • Catheter vascular access is also identified as a factor contributing to poor long-term prognosis.
  • These findings underscore the need for improved management strategies for hemodialysis patients.
Abstract

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