Related Experiment Video

Updated: Jun 5, 2026

Local Hyperthermia for Warts Treatment
04:25

Local Hyperthermia for Warts Treatment

Published on: November 8, 2024

2024 recommendations for the therapeutic management of anogenital warts

M Boyer1, M Boyer1, E Joly2

  • 1CHU La Réunion, Department of Infectious Diseases - Dermatology, Saint Pierre, La Réunion, France; UFR Santé (Health Training and Research Unit), University of La Réunion, France.

Annales De Dermatologie Et De Venereologie
|June 3, 2026
PubMed
Abstract

Insights

This study provides treatment recommendations for anogenital warts (AGW) by establishing a hierarchy of therapies based on a systematic literature review. It addresses various patient groups and specific treatment sites, promoting combination therapy.

Area of Science:

  • Dermatology
  • Infectious Diseases
  • Public Health

Background:

  • Anogenital warts (AGW) are common skin lesions caused by human papillomavirus (HPV).
  • AGW frequently recur after treatment, and existing guidelines lack treatment prioritization.
  • Therapies for AGW are categorized as self-administered or clinician-applied.

Purpose of the Study:

  • To develop evidence-based recommendations for managing anogenital warts (AGW).
  • To establish a prioritized hierarchy of treatments for AGW.
  • To provide guidance for diverse patient populations and specific anatomical sites.

Main Methods:

  • A systematic literature review was conducted by a working group with no conflicts of interest.
  • Databases searched included PubMed and Embase up to June 1, 2024.
  • Study quality was assessed using multiple standardized tools (PRISMA, ROBIS, AMSTAR 2, AGREE II, RIGHT, ROB grids) and expert review (GRaAL method).

Main Results:

  • 204 studies were selected from 1446, encompassing RCTs, SRs, non-randomized trials, MAs, and guidelines.
  • Methodological quality of the included studies varied significantly.
  • A treatment hierarchy algorithm was developed, considering general populations, pregnant women, children, immunocompromised individuals, and specific sites (urethral, vaginal, anal). Combination therapy is frequently recommended.

Conclusions:

  • These recommendations offer a structured approach to AGW management.
  • The hierarchy is based on a comprehensive systematic review of available literature.
  • Acknowledges limitations due to data gaps in specific populations and study quality variations.
Keywords:
Anogenital wartsGenital wartsHPVRecommendationsSystematic reviewTreatment

More Related Videos

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Related Concept Videos

Genital Herpes01:23

Genital Herpes

Genital herpes is a sexually transmitted infection primarily caused by herpes simplex virus type 2 (HSV-2), though herpes simplex virus type 1 (HSV-1) is increasingly implicated in genital infections, particularly among younger populations. Transmission occurs mainly through sexual contact, with asymptomatic viral shedding serving as a major route of spread. This characteristic makes HSV-2 difficult to control at a population level, as individuals may unknowingly transmit the virus even in the...
Sexually Transmitted Infections01:26

Sexually Transmitted Infections

Sexually transmitted infections (STIs) are diseases transmitted primarily through unsafe sexual interactions. Bacteria, viruses, or parasites cause them and can result in severe health complications if untreated.ChlamydiaThe bacterium Chlamydia trachomatis is responsible for the disease Chlamydia, the most common STI in the United States. This peculiar pathogen requires human cells to reproduce, residing intracellularly. The initial infection often goes unnoticed because it typically does not...
Trichomoniasis01:18

Trichomoniasis

Trichomonas vaginalis is a flagellated protozoan parasite and the causative agent of trichomoniasis, one of the most prevalent non-viral sexually transmitted infections in the United States. This extracellular parasite primarily colonizes the lower genitourinary tract in women—particularly the vagina—and in men, the urethra and prostate. Its structural and functional adaptations enable its survival, motility, and pathogenicity within the host environment.Structural Features and Host EntryT.
Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
Urinary Tract Infection IV: Nursing Management01:17

Urinary Tract Infection IV: Nursing Management

In managing urinary tract infections (UTIs) in nursing, a comprehensive assessment is essential. Begin by gathering subjective data, such as the patient’s complaints of dysuria (painful urination), urinary frequency, urgency, suprapubic pain, and any lower abdominal discomfort. This information can be complemented by questions regarding previous UTIs, sexual activity, and personal hygiene practices, which can provide insight into risk factors. Objective assessment should focus on signs like...
Peptic Ulcer Disease IV: Management01:26

Peptic Ulcer Disease IV: Management

Medical treatment strategies for peptic ulcers encompass various methods. The primary goal of treatment is to diminish gastric acidity and strengthen mucosal defense mechanisms.
The therapeutic approach involves ensuring adequate rest, implementing drug therapy, promoting smoking cessation, making dietary modifications, and emphasizing long-term follow-up care.
Pharmacological management
The prevailing therapy for peptic ulcers involves a combination of managing the patient's current medication...