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Related Experiment Video

Updated: Jun 5, 2026

Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material
07:42

Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material

Published on: December 20, 2024

Ex-vivo study investigating modified pulp-capping glass-ionomers.

Jirachaya Somudorn1, Hathaitip Sritanaudomchai2, Puangwan Lapthanasupkul3

  • 1Department of Operative Dentistry and Endodontics, Faculty of Dentistry, Mahidol University.

Dental Materials Journal
|June 3, 2026
PubMed
Summary

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Comparison of mineral precipitation, elemental release, pH change and cytotoxicity of calcium-silicate cements and an experimental resin-modified glass ionomer cement containing bioactive glass.

Biomaterial investigations in dentistry·2026
This summary is machine-generated.

Incorporating bioactive glass into glass-ionomer cement (GIc) shows promise for pulp capping. While promoting healing, its mineralization potential needs further optimization compared to calcium-silicate cements.

Area of Science:

  • Biomaterials Science
  • Dental Materials
  • Regenerative Dentistry

Background:

  • Pulp capping aims to preserve dental pulp vitality.
  • Glass-ionomer cement (GIc) is a common dental restorative material.
  • Bioactive glasses (BGs) show potential for stimulating hard tissue formation.

Purpose of the Study:

  • To evaluate the efficacy of bioactive glass-modified GIc as a pulp-capping agent.
  • To compare the pulpal healing response to BGs, β-tricalcium phosphate (TCP), ProRoot MTA, and Biodentine.
  • To assess mineralization and tissue organization in a human tooth-pulp culture model.

Main Methods:

  • Human tooth-pulp cultures were capped with GIc modified with BGs (45S5, 45S5.5Zn, 45S5.5Sr), TCP, ProRoot MTA, or Biodentine.
  • Unmodified GIc and Biodentine served as controls.
Keywords:
Bioactive glassBiodentineGlass ionomerMineral trioxide aggregateTooth-pulp culture model

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Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
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Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

Related Experiment Videos

Last Updated: Jun 5, 2026

Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material
07:42

Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material

Published on: December 20, 2024

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

  • Histological assessment of pulpal healing and mineral foci formation after 28 days.

    • Main Results:

    • Pulp mineralization was initiated only with GIc45S5 and Biodentine.
    • Bioactive glass-modified GIcs exhibited biocompatibility and early pulpal healing.
    • Mineralization potential of BG-modified GIcs was lower than Biodentine.

    Conclusions:

    • GIc45S5 shows potential as a preclinical pulp-capping material.
    • Further optimization of bioactive glass incorporation in GIc is needed for enhanced bioactivity.
    • Calcium-silicate cements like Biodentine demonstrate superior mineralization potential.