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Updated: Jun 5, 2026

The Motivation for Alcohol Reward: Predictors of Progressive-Ratio Intravenous Alcohol Self-Administration in Humans
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Variability in breath alcohol concentration profiles during controlled social drinking.

Ryan S O'connor1, Jennifer Wang1, Jay R Vargas1

  • 1School of Criminal Justice and Criminalistics, California State University Los Angeles, 5151 State University Drive, Los Angeles, CA 90032, United States.

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Summary

This study examined breath alcohol concentration (BrAC) during social drinking, finding varied absorption and elimination patterns. Results offer context for interpreting alcohol levels in real-world scenarios.

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Area of Science:

  • Pharmacology
  • Toxicology
  • Forensic Science

Background:

  • Controlled alcohol studies typically use standardized conditions.
  • Real-world social drinking involves variable consumption and food intake.
  • Understanding breath alcohol concentration (BrAC) variability is crucial.

Purpose of the Study:

  • To characterize BrAC profiles under supervised social drinking conditions.
  • To assess the impact of variable consumption and food intake on BrAC.
  • To provide context for interpreting alcohol measurements in applied settings.

Main Methods:

  • Forty-two adults consumed self-selected mixed drinks with ad libitum food access.
  • Drinking duration varied significantly (45-172 minutes).
  • BrAC was measured using an Intox EC/IR II until zero.

Main Results:

  • Peak BrAC ranged from 0.040 to 0.117 g/210 L.
  • Time to peak BrAC varied, with some delayed peaks observed.
  • Alcohol elimination was generally linear post-peak, with a mean rate of 0.0186 g/210 L/hr.

Conclusions:

  • Supervised social drinking yields diverse BrAC-time profiles.
  • Absorption timing can be variable, sometimes showing multi-peak patterns.
  • Findings enhance the interpretation of alcohol measurements in applied forensic and clinical settings.