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Clonal Hematopoiesis does not influence manufacturing of Chimeric Antigen Receptor (CAR) T-Cells

Simon M Krauß1,2, Konstantin Weibl1,2, Enrica Bach1,2

  • 1Department of Hematology, Cell Therapy, Hemostaseology and Infectiology, University of Leipzig Medical Center, Leipzig, Germany.

Bone Marrow Transplantation
|June 3, 2026
PubMed
Abstract

No abstract available in PubMed .

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T Cell Activation and Clonal Selection01:22

T Cell Activation and Clonal Selection

T cells are integral to our adaptive immune system, recognizing and effectively responding to foreign antigens. T cell activation and clonal selection are pivotal in orchestrating this immune response. This article elucidates these mechanisms, detailing the roles of cluster of differentiation (CD) markers, major histocompatibility complex (MHC) molecules, costimulatory signals, and the process of clonal selection.
Naive T cells that have not yet encountered an antigen express two primary CD...

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