Cancer-Critical Genes II: Tumor Suppressor Genes
Cancer-Critical Genes II: Tumor Suppressor Genes
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Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
Published on: July 5, 2019
Toshio Kokuryo1, Takashi Mizuno, Shunsuke Onoe
1Dept. of Surgery, Division of Hepatobiliary-Pancreatic Surgery, Nagoya University Hospital.
Fibroblast growth factor receptor 2 (FGFR2) fusions drive various cancers. Approved FGFR inhibitors show efficacy but resistance emerges, necessitating novel targeted therapies for improved outcomes.
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