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Updated: Jun 5, 2026
08:34
Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies
Published on: February 6, 2019
Journey through technological advancements in radiation therapy
Pratibha Singh1,2, Manoj Kumar Singh1, Atul Mishra3
1Department of Physics, Institute of Applied Sciences and Humanities, GLA University, Mathura 281406, Uttar Pradesh, India.
World Journal of Radiology
|June 4, 2026
Summary
Radiation therapy (RT) has evolved significantly, with modern innovations enhancing precision and safety. Future research focuses on AI, real-time tracking, and personalized treatments to improve patient outcomes.
Area of Science:
- Medical Physics
- Oncology
- Radiotherapy Technology
Background:
- Radiation therapy (RT) has seen major technological advancements since the first medical linear accelerator.
- These innovations have progressively improved treatment precision, efficiency, and patient safety in cancer care.
Purpose of the Study:
- To provide a comprehensive review of the historical evolution of RT technologies.
- To examine current research and future directions in radiotherapy innovation.
Main Methods:
- A systematic literature search was performed across PubMed, Scopus, and Web of Science.
- Included studies covered historical milestones, technological developments, clinical applications, and emerging research in RT.
Main Results:
- RT has advanced from early models to high-precision platforms with image guidance, adaptive techniques, and motion management.
- Recent developments include AI, magnetic resonance-guided RT, and personalized treatment modeling.
- Future research priorities include real-time tumor tracking, AI-driven decision support, and advanced delivery systems.
Conclusions:
- Radiation therapy has undergone transformative growth, continuously improving from its origins to state-of-the-art systems.
- Ongoing research and clinical validation are crucial for integrating new innovations and enhancing patient outcomes.
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