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Updated: Jun 5, 2026

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
12:18

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft

Published on: August 8, 2020

Two-stage Reconstruction of Acute Extensive Third-degree Burn Using Biodegradable Temporizing Matrix (NovoSorb BTM)

José Antonio López Martínez1, Jordi Serracanta Domenech1, Antonio Bulla1

  • 1From the Burn Unit, Department of Plastic, Reconstructive, and Aesthetic Surgery, Vall d'Hebron University Hospital, Barcelona, Spain.

Plastic and Reconstructive Surgery. Global Open
|June 4, 2026
PubMed
Summary

Biodegradable Temporizing Matrix (BTM) effectively closed large, deep burns, promoting neodermis regeneration and reducing infection risk. This synthetic alternative led to good functional recovery and scar quality in a high-risk patient.

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Burn Injuries01:22

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...