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Related Concept Videos

Diabetes: Management and Pharmacotherapy01:15

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...
Diabetes Mellitus: Type 2 and Gestational01:22

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
Diabetes Mellitus: Overview and Type I Subtype01:22

Diabetes Mellitus: Overview and Type I Subtype

Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...
Type II Diabetes I: Introduction01:26

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...
Atherosclerosis III: Management01:26

Atherosclerosis III: Management

Management of atherosclerosis involves an integrated strategy encompassing pharmacological treatment, surgical interventions, lifestyle changes, and nutrition therapy to address the multifactorial nature of the disease.Pharmacological TherapyA cornerstone of atherosclerosis management is the use of pharmacological agents. Statins, such as atorvastatin, are pivotal in inhibiting HMG-CoA reductase, an enzyme that catalyzes an initial step in cholesterol synthesis in the liver. This reduction in...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...

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Updated: Jun 5, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
10:03

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

Published on: February 28, 2013

Type 1 Diabetes and Cardiovascular Risk: The Current Management Strategies.

Rohit Jacob Manoj1, Aarthy Aravind2, Cornelius J Fernandez3

  • 1Department of Internal Medicine, Aster DM Healthcare, 8703 Dubai, U.A.E.

Reviews in Cardiovascular Medicine
|June 4, 2026
PubMed
Summary
This summary is machine-generated.

Cardiovascular disease (CVD) risk differs among diabetes types. This review focuses on evaluating and managing CVD in type 1 diabetes mellitus (T1DM), where uncertainties remain despite potential mitigation through metabolic control.

Keywords:
cardiovascular diseasecardiovascular disease riskdouble diabetesmetabolic controltype 1 diabetes mellitus

Related Experiment Videos

Last Updated: Jun 5, 2026

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory
10:03

A Zebrafish Model of Diabetes Mellitus and Metabolic Memory

Published on: February 28, 2013

Area of Science:

  • Endocrinology
  • Cardiology
  • Metabolic Diseases

Background:

  • Cardiovascular disease (CVD) is a leading cause of mortality in diabetes patients.
  • CVD risk varies significantly across different diabetes mellitus types due to distinct pathobiological mechanisms.
  • While CVD in type 2 diabetes mellitus (T2DM) is well-studied, significant knowledge gaps exist for type 1 diabetes mellitus (T1DM).

Purpose of the Study:

  • To review the current evidence for evaluating and managing cardiovascular disease (CVD) in patients with type 1 diabetes mellitus (T1DM).
  • To address uncertainties regarding the pathophysiology and prognosis of CVD in T1DM.
  • To provide a clinical update for healthcare professionals managing T1DM patients at risk for CVD.

Main Methods:

  • Systematic review of existing clinical evidence.
  • Analysis of epidemiological data on CVD prevalence in T1DM.
  • Synthesis of current guidelines and research findings on T1DM and CVD.

Main Results:

  • Type 1 diabetes mellitus (T1DM) typically presents with symptoms and has a lower initial CVD risk compared to T2DM.
  • Good metabolic control can mitigate CVD risk in T1DM to some extent.
  • Significant uncertainties persist regarding CVD pathophysiology and prognosis specifically in the T1DM population.

Conclusions:

  • Cardiovascular disease (CVD) evaluation and management in type 1 diabetes mellitus (T1DM) requires further research and clinical attention.
  • Understanding the unique aspects of CVD in T1DM is crucial for improving patient outcomes.
  • This review compiles current knowledge to guide clinical practice for CVD in T1DM.