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Epilepsy and Cluster C Personality Disorders: A Saudi Cross-Sectional Study
Mohammed A Aljaffer1, Ahmad H Almadani1, Ayedh H Alghamdi1
1Department of Psychiatry, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Neurosciences (Riyadh, Saudi Arabia)
|June 4, 2026
Summary
Cluster C personality disorders (PDs) affect 30.6% of epilepsy patients, with lower education and unemployment being risk factors. Early screening for PDs in epilepsy patients is recommended for better outcomes.
Area of Science:
- Neurology
- Psychiatry
Background:
- Epilepsy is a neurological disorder with significant life impacts.
- It is associated with medical and psychiatric comorbidities, including personality disorders (PDs).
Purpose of the Study:
- To assess the prevalence of Cluster C personality disorders (PDs) in adult patients with epilepsy (PWE).
- To identify factors associated with PDs in this population.
Main Methods:
- A cross-sectional study involving 360 adult PWE at a tertiary care hospital.
- Data collected using the Structured Clinical Interview for DSM Disorders criteria and custom questionnaires.
Main Results:
- Cluster C PDs were found in 30.6% of PWE.
- Obsessive-compulsive PD (17.8%) and avoidant PD (9.7%) were most common.
- Lower educational level, unemployment, and longer epilepsy duration were significantly associated with PDs.
Conclusions:
- Cluster C PDs are prevalent in PWE.
- Educational level, employment status, and epilepsy duration are associated with PDs.
- Screening for PDs in PWE is crucial for early detection and intervention.
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